Keywords
Aerobic Exercise
Hematocrit
HIV Seropositivity
How to Cite
Abstract
Background: Aerobic exercise is used to optimize the level of physical fitness and maintain normal systemic body functions while resistance exercise increases the concentration of various growth-promoting agents in the body that may contribute to these improved functions. Hence, increases haematological profile and blood serology, and blood distribution become more efficient. Objectives: This study was designed to examine the effects of 6-week aerobic and resistance exercise training programmes on the hematological profile of HIV-Seropositive subjects. Method: The pretest-posttest experimental and control groups design was adopted. Sixty female HIV-Seropositive subjects in stage 1 and 2 registered in the University of Benin Teaching Hospital participated in the study. They were randomly assigned into control and experimental groups. The experimental group exercised for one hour per session, three times a week for six weeks while the control group continued with their regular medications and counseling. The baseline intensity of exercise was 60% Heart Rate Reserve (HRR) and 60% one-repetition and the intensity was increased by 10% every 2 weeks. Hematological profiles were recorded at the baseline and on completion of 6 weeks for both groups. The hypotheses were tested with inferential statistics of Analysis of variance. Results: The findings of this study revealed that the hematological parameters of white blood cell (WBC) (p-value=.000), red blood cell (RBC)(p-value=.000) and haematocrit (HCT) (p-value=.002) were significantly improved while the platelet (p-value=.735) was not significant in female HIV-Seropositive subjects after six weeks exercise training. Conclusions: It was therefore concluded that short duration aerobics and resistance exercise training is of immense health benefits for female HIV- infected patients in terms of improved physical fitness and blood components.
References
Pescatello, L. S., D. Riebe & P. D. Thompson, ACSM's guidelines for exercise testing and prescription. 2014: Lippincott Williams & Wilkins.
Chetty, L., S. Cobbing & V. Chetty. Physical activity and exercise for older people living with HIV: a protocol for a scoping review. Syst Rev. 2020; 9(1): 1-6. https://doi.org/10.1186/s13643-020-01327-4.
Farrell III, J. W., D. J. Lantis, C. J. Ade, D. A. Bemben & R. D. Larson. Metabolic Response to Four Weeks of Muscular Endurance Resistance Training. Int J Kinesiol Sports Sci. 2017; 5(4): 10-17. http://dx.doi.org/10.7575/aiac.ijkss.v.5n.4p.10.
Grace, J. M., S. J. Semple & S. Combrink. Exercise therapy for human immunodeficiency virus/AIDS patients: Guidelines for clinical exercise therapists. J Exerc Sci Fit. 2015; 13(1): 49-56. https://doi.org/10.1016/j.jesf.2014.10.003.
Shadrin, I., A. Khodabukus & N. Bursac. Striated muscle function, regeneration, and repair. Cell Mol Life Sci. 2016; 73(22): 4175-4202. https://doi.org/10.1007/s00018-016-2285-z.
Hosseinzadeh, K. High Intensity Interval Training in Elderly Could Improve Elderly Health Significantly. Int J Aging Health Mov. 2019; 1(1): 10-11.
Ratamess, N., B. Alvar, T. Evetoch, T. Housh, W. Kibler & W. Kraemer. Progression models in resistance training for healthy adults [ACSM position stand]. Med Sci Sports Exerc. 2009; 41(3): 687-708. https://doi.org/10.1249/MSS.0b013e3181915670.
Crystal, S., J. A. Fleishman, R. D. Hays, M. F. Shapiro & S. A. Bozzette. Physical and role functioning among persons with HIV: results from a nationally representative survey. Med Care. 2000; 38(12): 1210-1223. https://doi.org/10.1097/00005650-200012000-00008.
Phillips, K. D. Physiological and psychological effects of exercise interventions in HIV disease. AIDS Patient Care. 2004; 18(2): 81. https://doi.org/10.1089/108729104322802515.
Gomes-Neto, M., C. S. Conceiçao, V. O. Carvalho & C. Brites. A systematic review of the effects of different types of therapeutic exercise on physiologic and functional measurements in patients with HIV/AIDS. Clinics. 2013; 68(8): 1157-1167. http://dx.doi.org/10.6061/clinics/2013(08)16.
Bhattacherjee, A., Social science research: Principles, methods, and practices. 2012, University of South Florida: Global Text Project.
Xi, E.-P. Percutaneous closure of a post-traumatic ventricular septal defect with a patent ductus arteriosus occluder. Clinics. 2012; 67(11): 1281-1283. https://doi.org/10.6061/clinics/2012(11)10.
Anastos, K., Q. Shi, A. L. French, A. Levine, R. M. Greenblatt, C. Williams, J. DeHovitz, R. Delapenha & D. R. Hoover. Total lymphocyte count, hemoglobin, and delayed-type hypersensitivity as predictors of death and AIDS illness in HIV-1–infected women receiving highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2004; 35(4): 383-392. https://doi.org/10.1097/00126334-200404010-00008.
Obirikorang, C. & F. A. Yeboah. Blood haemoglobin measurement as a predictive indicator for the progression of HIV/AIDS in resource-limited setting. J Biomed Sci. 2009; 16(1): 102. https://doi.org/10.1186/1423-0127-16-102.
Wardyn, G. G., S. I. Rennard, S. K. Brusnahan, T. R. McGuire, M. L. Carlson, L. M. Smith, S. McGranaghan & J. G. Sharp. Effects of exercise on hematological parameters, circulating side population cells, and cytokines. Exp Hematol. 2008; 36(2): 216-223. https://doi.org/10.1016/j.exphem.2007.10.003.
Munyazesa, E., I. Emile, E. Mutimura, D. R. Hoover, Q. Shi, A. P. McGinn, S. Musiime, F. Muhairwe, A. Rutagengwa & J. C. Dusingize. Assessment of haematological parameters in HIV-infected and uninfected Rwandan women: a cross-sectional study. BMJ open. 2012; 2(6): 1-7. https://doi.org/10.1136/bmjopen-2012-001600.
Azuonwu, O., N. Frank-Peterside, S. Ibe & O. Erhabor. Correlates between HIV/AIDS Antibody with some Immuno-Hematological Variables of Infected Subjects in Niger Delta Communities. J Appl Pharm Sci. 2012; 2(8): 85. https://doi.org/10.7324/japs.2012.2813.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.